Article
The influence of serum apolipoprotein E concentration and polymorphism on serum lipid parameters in hemodialysis patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Aug 2004
Liberopoulos Evagelos N, Miltiadous George A, Cariolou Marios, Tselepis Alexandros D, Siamopoulos Kostas C, Elisaf Moses S
Abstract excerpt
BACKGROUND: Apolipoprotein E (ApoE) polymorphism has been shown to influence serum lipid parameters and ApoE levels in both healthy subjects and hemodialysis (HD) patients. Conversely, ApoE concentration significantly affects serum lipid levels in the general population, independently of ApoE polymorphism, by modulating lipoprotein production, lipolytic conversion, and receptor-mediated clearance. Therefore,...
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