Article
Novel quantitative trait locus is mapped to chromosome 12p11 for left ventricular mass in Dominican families: the Family Study of Stroke Risk and Carotid Atherosclerosis.
BMC medical genetics - 23 Jul 2009
Wang Liyong, Beecham Ashley, Di Tullio Marco R, Slifer Susan, Blanton Susan H, Rundek Tatjana, Sacco Ralph L
Abstract excerpt
BACKGROUND: Left ventricular mass (LVM) is an important risk factor for stroke and vascular disease. The genetic basis of LVM is unclear although a high heritability has been suggested. We sought to map quantitative trait loci (QTL) for LVM using large Dominican families. METHODS: Probands were selected from Dominican subjects of the population-based Northern Manhattan Study (NOMAS). LVM was measured by...
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