Article
Association of the ScaI atrial natriuretic peptide gene polymorphism with nonfatal myocardial infarction and extent of coronary artery disease.
American heart journal - 1 Jan 2003
Gruchala Marcin, Ciećwierz Dariusz, Wasag Bartosz, Targoński Radoslsoław, Dubaniewicz Witold, Nowak Arkadiusz, Sobiczewski Wojciech, Ochman Karolina, Romanowski Piotr, Limon Janusz, Rynkiewicz Andrzej
Abstract excerpt
BACKGROUND: There is growing evidence from recent studies that atrial natriuretic peptide (ANP) plays an important part in coronary blood flow regulation and in atherosclerosis. Transition T2238-->C in the atrial natriuretic peptide (ANP) precursor gene, which leads potentially to the translation of ANP with 2 additional arginines, has been suggested to be associated with salt-sensitive hypertension. According to...
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