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Article

Myocardial infarction is associated with Spl binding site polymorphism of collagen type 1A1 gene.

Acta cardiologica - 1 Jun 2006

Speer Gábor, Szenthe Péter, Kósa János P, Tabák Adám G, Folhoffer Anikó, Fuszek Péter, Cseh Károly, Lakatos Péter

Abstract excerpt

OBJECTIVE: Human atherosclerotic lesions contain collagen type I, which plays a pivotal role in atherosclerotic plaque stability. In contrast, the normal coronary arteries do not express this type of collagen. Data have shown that the collagen type 1A1 (COL1A1) gene Sp1 binding site (-1245 G/T) polymorphism is associated with disturbed collagen protein production. METHODS: In our study, COL1A1 gene Sp1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16869454
DOI: 10.2143/AC.61.3.2014835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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