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Article

Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking.

Human molecular genetics - 15 Oct 2009

Hsiao Yi-Chun, Tong Zachary J, Westfall Jennifer E, Ault Jeffrey G, Page-McCaw Patrick S, Ferland Russell J

Abstract excerpt

The primary non-motile cilium, a membrane-ensheathed, microtubule-bundled organelle, extends from virtually all cells and is important for development. Normal functioning of the cilium requires proper axoneme assembly, membrane biogenesis and ciliary protein localization, in tight coordination with the intraflagellar transport system and vesicular trafficking. Disruptions at any level can induce severe...

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Identifiers

PMID: 19625297
DOI: 10.1093/hmg/ddp335
PMCID: PMC2748898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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