Article
Unusual presentation of severe intrahepatic cholestasis of pregnancy leading to fetal death.
Obstetrics and gynecology - 1 Aug 2009
Favre Nathalie, Abergel Armand, Blanc Pierre, Sapin Vincent, Roszyk Laurence, Gallot Denis
Abstract excerpt
BACKGROUND: We report an unusual presentation of intrahepatic cholestasis of pregnancy complicated by fetal death and associated with homozygous bile salt export pump polymorphism. CASE: A secundigravida presented at 31 weeks of pregnancy with discrete pruritus and highly elevated bile acid levels (223 micromol/L) suggestive of intrahepatic cholestasis of pregnancy, despite normal serum aminotransferase levels....
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