Article
Biological and immunological characteristics of hepatitis E virus-like particles based on the crystal structure.
Proceedings of the National Academy of Sciences of the United States of America - 4 Aug 2009
Yamashita Tetsuo, Mori Yoshio, Miyazaki Naoyuki, Cheng R Holland, Yoshimura Masato, Unno Hideaki, Shima Ryoichi, Moriishi Kohji, Tsukihara Tomitake, Li Tian Cheng, Takeda Naokazu, Miyamura Tatsuo, Matsuura Yoshiharu
Abstract excerpt
Hepatitis E virus (HEV) is a causative agent of acute hepatitis. The crystal structure of HEV-like particles (HEV-LP) consisting of capsid protein was determined at 3.5-A resolution. The capsid protein exhibited a quite different folding at the protruding and middle domains from the members of th...
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