Article
Cognitive flexibility is associated with KIBRA variant and modulated by recent tobacco use.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Nov 2009
Zhang Huiping, Kranzler Henry R, Poling James, Gruen Jeffrey R, Gelernter Joel
Abstract excerpt
The kidney and brain expressed protein gene (KIBRA) and the calsyntenin 2 gene (CLSTN2) are reportedly involved in synaptic plasticity. Single nucleotide polymorphisms (SNPs) rs17070145 (KIBRA) and rs6439886 (CLSTN2) have been found to affect memory performance measures. This study examined the association of KIBRA SNP rs17070145 and CLSTN2 SNPs rs6439886 and rs17348572 (a nonsynonymous variant) with cognitive...