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Article

Discordance in human paraoxonase-1 gene between phenotypes and genotypes in chronic kidney disease.

Nephron. Clinical practice - 1 Jan 2009

Paragh Gyorgy, Seres Ildiko, Harangi Mariann, Pocsai Zsuzsa, Asztalos Laszlo, Locsey Lajos, Szeles Gyorgy, Kardos Laszlo, Varga Eva, Karpati Istvan, Adany Roza

Abstract excerpt

BACKGROUND: Human serum paraoxonase-1 (PON1) is a high-density lipoprotein-associated ester hydrolase which can inhibit low-density lipoprotein oxidation and has an antiatherogenic effect. Two common polymorphisms are known in the PON1 gene in humans (at positions 55 and 192), from which the latter gene alteration has been mainly attributed to alter the activity of the protein. Moreover, significantly reduced...

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Identifiers

PMID: 19602899
DOI: 10.1159/000228075

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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