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Article

HDL3-related decreased serum paraoxonase (PON) activity in uremic patients: comparison with the PON1 allele polymorphism.

Clinica chimica acta; international journal of clinical chemistry - 1 Oct 2002

Schiavon Renzo, Battaglia Paolo, De Fanti Emanuela, Fasolin Antonio, Biasioli Stefano, Targa Lino, Guidi Giancesare

Abstract excerpt

BACKGROUND: Patients with chronic renal failure on maintenance haemodialysis (HD) are at high risk of atherothrombotic events; an enhanced oxidant stress might have a major role. The decrease of human paraoxonase (PON1), an anti-oxidant high-density lipoprotein (HDL)-linked enzyme, is a possible mechanism for developing cardiovascular disease. To ascertain the causes of low PON1 in such patients, we investigated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Kidney Failure, Chronic

Share to Lipoproteins, HDL

Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 12204423
DOI: 10.1016/s0009-8981(02)00216-4

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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