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Article

Chloroquine and sulphadoxine-pyrimethamine sensitivity of Plasmodium falciparum parasites in a Brazilian endemic area.

Malaria journal - 14 Jul 2009

Gama Bianca Ervatti, de Oliveira Natália K Almeida, Zalis Mariano G, de Souza José Maria, Santos Fátima, Daniel-Ribeiro Cláudio Tadeu, Ferreira-da-Cruz Maria de Fátima

Abstract excerpt

BACKGROUND: The goal of the present study was the characterization of Plasmodium falciparum genes associated to malaria drug resistance (pfcrt, pfdhfr and pfdhps), in samples from two Brazilian localities. METHODS: Parasites from 65 P. falciparum samples were genotyped using nested-PCR and direct DNA sequencing. RESULTS: Six resistant sulphadoxine-pyrimethamine (SP) pfdhfr genotypes and one haplotype associated...

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Identifiers

PMID: 19602248
DOI: 10.1186/1475-2875-8-156
PMCID: PMC2716359

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