Article
Chloroquine and sulphadoxine-pyrimethamine sensitivity of Plasmodium falciparum parasites in a Brazilian endemic area.
Malaria journal - 14 Jul 2009
Gama Bianca Ervatti, de Oliveira Natália K Almeida, Zalis Mariano G, de Souza José Maria, Santos Fátima, Daniel-Ribeiro Cláudio Tadeu, Ferreira-da-Cruz Maria de Fátima
Abstract excerpt
BACKGROUND: The goal of the present study was the characterization of Plasmodium falciparum genes associated to malaria drug resistance (pfcrt, pfdhfr and pfdhps), in samples from two Brazilian localities. METHODS: Parasites from 65 P. falciparum samples were genotyped using nested-PCR and direct...
Topics
- Animals
- Antimalarials
- Brazil
- Chloroquine
- Drug Combinations
- Drug Resistance
- Endemic Diseases
- Haplotypes
- Humans
- Malaria, Falciparum
- Parasitic Sensitivity Tests
- Plasmodium falciparum
- Polymerase Chain Reaction
- Polymorphism, Single Nucleotide