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Article

The acrosomal protein Dickkopf-like 1 (DKKL1) facilitates sperm penetration of the zona pellucida.

Fertility and sterility - 15 Mar 2010

Kohn Matthew J, Sztein Jorge, Yagi Rieko, DePamphilis Melvin L, Kaneko Kotaro J

Abstract excerpt

OBJECTIVE: To determine the role of Dkkl1 in mouse development, viability, and fertility. DESIGN: Prospective experimental study. SETTING: Government research institution. ANIMAL(S): Mice of C57BL/6, B6D2F1/J, and 129X1/SvJ strains, as well as transgenic mice of mixed C57BL/6 and 129X1/SvJ strains were used for the studies. INTERVENTION(S): Expression of the Dkkl1 gene was characterized during early mouse...

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Source

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Identifiers

PMID: 19596312
DOI: 10.1016/j.fertnstert.2009.06.010
PMCID: PMC2838937

Genes

DKKL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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