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First molecular genotyping of voltage gated sodium channel alleles in Culex quinquefasciatus populations in Malaysia.

Pesticide biochemistry and physiology - 1 Sept 2013

Low V L, Chen C D, Lim P E, Lee H L, Tan T K, Lim Yvonne A L, Sofian-Azirun M

Abstract excerpt

A nationwide investigation was performed to detect the presence of 1014 mutation(s) in voltage gated sodium channel (kdr) gene of Culex quinquefasciatus from 14 residential areas across 13 states and a federal territory in Malaysia. Molecular genotyping of kdr mutation was performed via a modified three tubes allele-specific-polymerase chain reaction (AS-PCR) and direct sequencing of kdr gene. Based on the...

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PMID: 25149246
DOI: 10.1016/j.pestbp.2013.06.004

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