Article
Stress-induced galectin-1 influences immune tolerance in the spleen and thymus by modulating CD45 immunoreactive lymphocytes.
The journal of physiological sciences : JPS - 1 Jul 2017
Sasaguri Kenichi, Yamada Kentaro, Narimatsu Yuri, Oonuki Masami, Oishi Azusa, Koda Koyo, Kubo Kin-Ya, Yamamoto Toshiharu, Kadoya Toshihiko
Abstract excerpt
Galectin-1 (Gal-1) is differentially expressed in normal and pathological tissues and regulates immune cell homeostasis. Restraint stress increases serum Gal-1 in rats. However, the function of stress-induced Gal-1 in serum is unknown. We determined if stress-induced Gal-1 in serum accumulates in immunocompetent organs as protection from physiological and/or psychological stress. Western blotting showed that the...
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