Article
The immune factors have complex causal regulation effects on bone mineral density.
Frontiers in immunology - 1 Jan 2022
Cao Rong-Rong, Yu Xing-Hao, Xiong Meng-Fei, Li Xue-Ting, Deng Fei-Yan, Lei Shu-Feng
Abstract excerpt
Recent evidence has gradually recognized that the immune and skeletal systems are two closely correlated systems, but the specific immune factors on bone mineral density (BMD) are largely unknown. Based on the summary-level data of genome-wide association studies (GWASs), we performed a series of analyses including two-sample Mendelian randomization (MR) analysis to test potential causal links between 731 immune...
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