Article
Use of SNP-arrays for ChIP assays: computational aspects.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Muro Enrique M, McCann Jennifer A, Rudnicki Michael A, Andrade-Navarro Miguel A
Abstract excerpt
The simultaneous genotyping of thousands of single nucleotide polymorphisms (SNPs) in a genome using SNP-Arrays is a very important tool that is revolutionizing genetics and molecular biology. We expanded the utility of this technique by using it following chromatin immunoprecipitation (ChIP) to assess the multiple genomic locations protected by a protein complex recognized by an antibody. The power of this...
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