Article
A simple, bead-based approach for multi-SNP molecular haplotyping.
Nucleic acids research - 6 Jan 2005
Hurley James D, Engle Linda J, Davis Jesse T, Welsh Adam M, Landers John E
Abstract excerpt
Single nucleotide polymorphisms (SNPs) within a gene region have often been studied to determine their effect on phenotype. Although a single base pair change can produce a phenotypic change, phenotype is often influenced by the presence of multiple polymorphisms and their relative positions within a given region. For example, if multiple changes occur in a promoter region, how they influence gene expression will...
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