A variation in the cerebroside sulfotransferase gene is linked to exercise-modified insulin resistance and to type 2 diabetes.

doi:10.1155/2009/429593

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Article

A variation in the cerebroside sulfotransferase gene is linked to exercise-modified insulin resistance and to type 2 diabetes.

Experimental diabetes research - 1 Jan 2009

Roeske-Nielsen A, Buschard K, Månson J E, Rastam L, Lindblad U

Abstract excerpt

AIMS: The glycosphingolipid beta-galactosylceramide-3-O-sulfate (sulfatide) is present in the secretory granules of the insulin producing beta-cells and may act as a molecular chaperone of insulin. The final step in sulfatide synthesis is performed by cerebroside sulfotransferase (CST) (EC 2.8.2.11). The aim of this study was to investigate whether two single nucleotide polymorphisms (SNP), rs2267161 located in...

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PMID: 19587831
DOI: 10.1155/2009/429593
PMCID: PMC2705865

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