Article
[Computational biology strategy for identification of complex disease genes].
Yi chuan = Hereditas - 1 Jun 2009
Wang Min, Zhang Shuang, Huang Qing-Yang
Abstract excerpt
For the past two decades, the dominant methods to identify susceptibility genes of complex disease were linkage analysis and association study. Linkage analysis usually identifies broad intervals, which can encompass dozens to hundreds of candidate genes. Transition from quantitative trait loci to gene has been a challenge due to the absence of complete functional information for the majority of genes in this...
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