Article
Mismatch DNA-specific enzymatic cleavage employed in a new method for the electrochemical detection of genetic mutations.
Chemical communications (Cambridge, England) - 28 Jul 2009
Won Byoung Yeon, Shin Sung Chul, Chung Won-young, Shin Sujeong, Cho Dae-Yeon, Park Hyun Gyu
Abstract excerpt
Utilizing enzymatic mismatched DNA-specific cleavage and electrocatalytic signaling, a new electrochemical method for the detection of DNA mutations was developed and successfully applied to detect various mutations in the BRCA1 gene.
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