Article
Lesion-induced hippocampal plasticity in transgenic Alzheimer's disease mouse models: influences of age, genotype, and estrogen.
Journal of Alzheimer's disease : JAD - 1 Jan 2009
Kadish Inga, van Groen Thomas
Abstract excerpt
We have studied entorhinal cortex lesion-induced sprouting in the hippocampus in young, adult, and aged control and transgenic Alzheimer's disease model mice. The entorhinal cortex was unilaterally, partially lesioned, and four weeks later the subsequent axonal sprouting in dentate gyrus was analyzed. Our data demonstrate that young and adult, control and amyloid-beta protein precursor (AbetaPP)/presenilin 1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
