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Article

Enrichment of Sca1+ hematopoietic progenitors in polycythemic mice inhibits leukemogenesis.

Blood - 27 Aug 2009

Usenko Tatiana, Li You-Jun, Haeri Mehran, Li Yanmei, Vecchiarelli-Federico Laura M, Zhao Xiaojun, Prchal Josef T, Ben-David Yaacov

Abstract excerpt

Polycythemia vera (PV) is a myeloproliferative disorder characterized by a pronounced increase in the number of erythroid cells. However, despite this aberrant proliferation, the incidence of erythroleukemia is paradoxically rare in PV patients. In this study, we show that the progression of Friend virus-induced erythroleukemia is delayed in a mouse model of primary familial congenital polycythemia in which the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19584401
DOI: 10.1182/blood-2008-11-187419

Genes

EPOR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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