Article
Combined histomorphologic and immunohistochemical phenotype to predict the presence of vascular invasion in colon cancer.
Diseases of the colon and rectum - 1 Jun 2009
Zlobec Inti, Höller Sylvia, Tornillo Luigi, Terracciano Luigi, Lugli Alessandro
Abstract excerpt
PURPOSE: Vascular invasion is an adverse prognostic factor in colorectal cancer and often is considered an indication for systemic adjuvant therapy. The aim of this study was to develop a predictive model of vascular invasion in a large cohort of colon cancers with use of tumor-related features and immunohistochemical analysis of protein markers. METHODS: A tissue microarray including 427 colon cancers was...
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