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Article

Preoperative prediction of perineural invasion and KRAS mutation in colon cancer using machine learning.

Journal of cancer research and clinical oncology - 1 Dec 2020

Li Yu, Eresen Aydin, Shangguan Junjie, Yang Jia, Benson Al B, Yaghmai Vahid, Zhang Zhuoli

Abstract excerpt

PURPOSE: Preoperative prediction of perineural invasion (PNI) and Kirsten RAS (KRAS) mutation in colon cancer is critical for treatment planning and patient management. We developed machine learning models for diagnosis of PNI and KRAS mutation in colon cancer patients by interpreting preoperative CT. METHODS: This retrospective study included 207 patients who received surgical resection in our institution. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32779023
DOI: 10.1007/s00432-020-03354-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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