Article
Multimarker phenotype predicts adverse survival in patients with lymph node-negative colorectal cancer.
Cancer - 1 Feb 2008
Zlobec Inti, Minoo Parham, Baumhoer Daniel, Baker Kristi, Terracciano Luigi, Jass Jeremy R, Lugli Alessandro
Abstract excerpt
BACKGROUND: The heterogeneity of stage II colon cancer underlines the need for identifying high-risk, lymph node-negative patients. The objective of this study was to define a multimarker prognostic model of 5-year survival in patients with lymph node-negative, mismatch repair (MMR)-proficient colorectal cancer (CRC). METHODS: Immunohistochemistry for 13 tumor markers was performed on 587 lymph node-negative,...
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