Article
Inter-laboratory evaluation of the bioluminescent Salmonella reverse mutation assay using 10 model chemicals.
Mutagenesis - 1 Sept 2009
Ackerman Joel, Sharma Rahul, Hitchcock Jonathan, Hayashi Toshiaki, Nagai Yoshikazu, Li Shuanglian, Lu Shuyan, Miret Juan, Tang Kim, Spence Fiona, Aubrecht Jiri
Abstract excerpt
We have developed the bioluminescent Salmonella reverse mutation assay as a tool for detecting mutagenicity applicable for high-throughput screening of new chemicals. In this study, we report the inter-laboratory evaluation of the assay using 10 model chemicals in five independent laboratories located in the USA (Groton, CT; Cambridge, MA and La Jolla, CA), Europe (Sandwich, Kent, UK) and Asia (Nagoya, Japan)....
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