Article
Mutation-prone positions within the estrogen receptor.
Taiwanese journal of obstetrics & gynecology - 1 Jun 2009
Wiwanitkit Viroj
Abstract excerpt
OBJECTIVE: Estrogen is an important female hormone. The estrogen receptor (ER) plays a critical role in the development of breast cancer. Mutations within the ER can have clinically significant consequences. MATERIALS AND METHODS: Identification of sites vulnerable to mutation is a new trend aimed at extending our knowledge of diseases at the genomic and proteomic levels. In this study, bioinformatics analysis...
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