Article
A computational algorithm for personalized medicine in schizophrenia.
Schizophrenia research - 1 Feb 2018
Lee Beom S, McIntyre Roger S, Gentle James E, Park Nan Sook, Chiriboga David A, Lee Yena, Singh Sabrina, McPherson Marie A
Abstract excerpt
Despite advances in sequencing candidate genes and whole genomes, no method has accurately predicted who will or will not benefit from a specific antipsychotic medication among patients with schizophrenia. We propose a computational algorithm that utilizes a person-centered approach that directly identifies individual patients who will respond to a specific antipsychotic medication. The algorithm was applied to...
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