Article
Maternal/newborn genotype contribution of the renin-angiotensin system (Met235Thr, Thr174Met, I/D-ACE, A2350G-ACE, A1166C-AT2R1, C3123A- AT2R2, 83A/G-REN) to the risk of pre-eclampsia: a Romanian study.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2011
Procopciuc Lucia Maria, Caracostea Gabriela, Zaharie Gabriela, Puscas Mariana, Iordache Georgiana, Popa Monica, Colcear Doina, Olteanu Ileana, Stamatian Florin
Abstract excerpt
INTRODUCTION: We evaluated the association of the mutated genotypes Met235Thr-AGT, Thr174Met-AGT, I/D-ACE, A2350G-ACE, A1166C-AT2R1, C3123A-AT2R2, (83)A/G-REN with the risk and outcome of pre-eclampsia; we also investigated whether genes in newborns increase maternal risk of pre-eclampsia. MATERIALS AND METHODS: Thirty-six pairs of pre-eclamptic women and their newborns were genotyped, along with 71 pairs of...
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