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Article

Physiological Thyroid Hormone Levels Regulate Numerous Skeletal Muscle Transcripts

1 Jul 2009

Abstract excerpt

CONTEXT: Skeletal muscle is an important target tissue for thyroid hormone (TH). It is currently unknown which genes are regulated by physiological TH levels. OBJECTIVE: We examined the effects of l-thyroxine on human skeletal muscle transcriptome. DESIGN: Microarray analysis of transcript levels was performed using skeletal muscle biopsies from patients under euthyroid and hypothyroid conditions. SETTING: The...

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PMID: 19567520
DOI: 10.1210/jc.2009-0782

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