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Article

Global gene expression profiles in skeletal muscle of monozygotic female twins discordant for hormone replacement therapy

30 Sept 2010

Abstract excerpt

Aging is accompanied by inexorable loss of muscle tissue. One of the underlying causes for this is the massive change in the hormonal milieu of the body. The role of a female sex steroid - estrogen - in these processes is frequently neglected, although the rapid decline in its production coincides with a steep deterioration in muscle performance. We recruited 54- to 62-year-old monozygotic female twin pairs...

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PMID: 20883525
DOI: 10.1111/j.1474-9726.2010.00636.x

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