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Article

H. pylori escape host immunoreaction through inhibiting ILK expression by VacA.

Cellular & molecular immunology - 1 Jun 2009

Yuan Jianping, Li Ping, Tao Jing, Shi Xiaodong, Hu Baoyu, Chen Huabiao, Guo Xiaokui

Abstract excerpt

Helicobacter pylori (H. pylori) persistently colonizes the gastric mucosa despite a vigorous immune response. Vacuolating cytotoxin secreted by H. pylori has turned out to be a potent immunomodulatory toxin, but the signal transduction pathways involved has not been studied in macrophages. We observed in this study that vacA-deficient H. pylori induced significantly higher expression of integrin-linked kinase...

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Share to Gene Expression Regulation, Enzymologic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Nitric Oxide Synthase Type III

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Source

Open in PubMed Open full text

Identifiers

PMID: 19567202
DOI: 10.1038/cmi.2009.26
PMCID: PMC4003062

Genes

ILK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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