Article
Primary lung cancer and TNF-alpha gene polymorphisms: a case-control study in a Croatian population.
Medical science monitor : international medical journal of experimental and clinical research - 1 Jul 2009
Flego Veljko, Radojcić Badovinac Andjelka, Bulat-Kardum Ljiljana, Matanić Dubravka, Crnić-Martinović Marija, Kapović Miljenko, Ristić Smiljana
Abstract excerpt
BACKGROUND: Tumor necrosis factor-alpha (TNF-alpha) is a multifunctional cytokine involved in the pathogenesis of various inflammatory and malignant diseases. Previous studies investigating the role of the TNF-alpha gene polymorphisms in lung cancer have generated contradictory results. The present study investigated whether the TNF-alpha-308 and TNF-alpha-238 polymorphisms are associated with risk and/or...
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