Article
Phenotype-dependent apoptosis signalling in mesothelioma cells after selenite exposure.
Journal of experimental & clinical cancer research : CR - 29 Jun 2009
Nilsonne Gustav, Olm Eric, Szulkin Adam, Mundt Filip, Stein Agnes, Kocic Branka, Rundlöf Anna-Klara, Fernandes Aristi P, Björnstedt Mikael, Dobra Katalin
Abstract excerpt
BACKGROUND: Selenite is a promising anticancer agent which has been shown to induce apoptosis in malignant mesothelioma cells in a phenotype-dependent manner, where cells of the chemoresistant sarcomatoid phenotype are more sensitive. METHODS: In this paper, we investigate the apoptosis signalling mechanisms in sarcomatoid and epithelioid mesothelioma cells after selenite treatment. Apoptosis was measured with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
