Article
Monitoring homologous recombination following replication fork perturbation in the fission yeast Schizosaccharomyces pombe.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Osman Fekret, Whitby Matthew C
Abstract excerpt
Replication forks (RFs) frequently encounter barriers or lesions in template DNA that can cause them to stall and/or break. Efficient genome duplication therefore depends on multiple mechanisms that variously act to stabilize, repair, and restart perturbed RFs. Integral to at least some of these mechanisms are homologous recombination (HR) proteins, but our knowledge of how they act to ensure high-fidelity genome...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
