Article
Association of functional polymorphisms in MMPs genes with gastric cardia adenocarcinoma and esophageal squamous cell carcinoma in high incidence region of North China.
Molecular biology reports - 1 Jan 2010
Li Yan, Sun Dong-lan, Duan Ya-nan, Zhang Xiao-juan, Wang Na, Zhou Rong-miao, Chen Zhi-feng, Wang Shi-jie
Abstract excerpt
The aim of the present study was to investigate the association of single nucleotide polymorphisms (SNPs) in matrix metalloproteinase (MMPs) with the risk of gastric cardia adenocarcinoma (GCA) and esophageal squamous cell carcinoma (ESCC). Genotypes were analyzed by polymerase chain reaction-restriction fragment-length polymorphism method in 592 patients and 624 healthy individuals. Significant differences in...
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