Article
Impact of interaction of polymorphic forms of p53 codon 72 and N-acetylation gene (NAT2) on the risk of lung cancer in the North Indian population.
DNA and cell biology - 1 Sept 2009
Sobti Ranbir C, Kaur Pushpinder, Kaur Satinder, Janmeja Ashok K, Jindal Surinder K, Kishan Jai, Raimondi Sara
Abstract excerpt
The interaction of genetic and environmental factors can determine individual susceptibility to various cancers. We studied the influence of NAT2 and codon 72 p53 polymorphisms on 151 patients with lung cancer and an equal number of matched population controls. Polymorphisms of NAT2 and p53 were determined by PCR-RFLP techniques. The results were analyzed using logistic regression analysis. A statistically...
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