Article
Polymorphism and selection in the major histocompatibility complex DRA and DQA genes in the family Equidae.
Immunogenetics - 1 Jul 2009
Janova Eva, Matiasovic Jan, Vahala Jiri, Vodicka Roman, Van Dyk Enette, Horin Petr
Abstract excerpt
The major histocompatibility complex genes coding for antigen binding and presenting molecules are the most polymorphic genes in the vertebrate genome. We studied the DRA and DQA gene polymorphism of the family Equidae. In addition to 11 previously reported DRA and 24 DQA alleles, six new DRA sequences and 13 new DQA alleles were identified in the genus Equus. Phylogenetic analysis of both DRA and DQA sequences...
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