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Article

Positive selection in the SLC11A1 gene in the family Equidae.

Immunogenetics - 1 May 2016

Bayerova Zuzana, Janova Eva, Matiasovic Jan, Orlando Ludovic, Horin Petr

Abstract excerpt

Immunity-related genes are a suitable model for studying effects of selection at the genomic level. Some of them are highly conserved due to functional constraints and purifying selection, while others are variable and change quickly to cope with the variation of pathogens. The SLC11A1 gene encodes a transporter protein mediating antimicrobial activity of macrophages. Little is known about the patterns of...

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PMID: 26846480
DOI: 10.1007/s00251-016-0905-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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