Article
Lymphoid Germinal Centers Are Reservoirs of Human Immunodeficiency Virus Type 1 RNA
1 Dec 1991
Abstract excerpt
When radiolabeled RNA was used for in situ hybridization, human immunodeficiency virus type 1 (HIV-1) RNA was found in high concentrations in germinal centers of lymphoid tissues from patients with HIV-1 infection. Most of the signal from hybridized probe was independent of specific cells, being found in the extracellular space of germinal centers in all lymphoid tissues examined from adult patients with Centers...
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