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Article

DNA deaminases: AIDing hormones in immunity and cancer.

Journal of molecular medicine (Berlin, Germany) - 1 Sept 2009

Petersen-Mahrt Svend K, Coker Heather A, Pauklin Siim

Abstract excerpt

It is well established that hormones can cause cancer, much less known is how they induce this change in our somatic cells. This review highlights the recent finding that estrogen can exert its DNA-damaging potential by directly activating DNA deaminases. This recently discovered class of proteins deaminate cytosine to uracil in DNA, and are essential enzymes in the immune system. The enhanced production of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19554301
DOI: 10.1007/s00109-009-0496-6
PMCID: PMC2727621

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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