Inhibition of angiogenesis by tissue inhibitor of metalloproteinase.

doi:10.1002/jcp.1041600122

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Article

Inhibition of angiogenesis by tissue inhibitor of metalloproteinase.

Journal of cellular physiology - 1 Jul 1994

Johnson M D, Kim H R, Chesler L, Tsao-Wu G, Bouck N, Polverini P J

Abstract excerpt

Matrix proteases play a critical role in cell invasion and migration, including the process of angiogenesis. The ability of specific factors to induce angiogenic responses correlates with their stimulation of matrix protease synthesis and release. Using an in vivo angiogenesis assay, the endothelial cell response to known angiogenic factors, basic fibroblast growth factor (bFGF) and adipocyte conditioned medium,...

Topics

Adipocytes
Animals
Blotting, Northern
Cattle
Cell Differentiation
Cell Movement
Cells, Cultured
Culture Media, Conditioned
Endothelium, Vascular
Fibroblast Growth Factor 2
Glycerides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Glycoproteins

Humans

In Vitro Techniques

Matrix Metalloproteinase Inhibitors

Neovascularization, Pathologic

Phenotype

Rats

Source

Open in PubMed

Identifiers

PMID: 7517405
DOI: 10.1002/jcp.1041600122

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7517405-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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