Article
A computational procedure to identify significant overlap of differentially expressed and genomic imbalanced regions in cancer datasets.
Nucleic acids research - 1 Aug 2009
Bicciato Silvio, Spinelli Roberta, Zampieri Mattia, Mangano Eleonora, Ferrari Francesco, Beltrame Luca, Cifola Ingrid, Peano Clelia, Solari Aldo, Battaglia Cristina
Abstract excerpt
The integration of high-throughput genomic data represents an opportunity for deciphering the interplay between structural and functional organization of genomes and for discovering novel biomarkers. However, the development of integrative approaches to complement gene expression (GE) data with other types of gene information, such as copy number (CN) and chromosomal localization, still represents a computational...
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