Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identifying associations between genomic alterations in tumors.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

George Joshy, Gorringe Kylie L, Smyth Gordon K, Bowtell David D L

Abstract excerpt

Single-nucleotide polymorphism (SNP) mapping arrays are a reliable method for identifying somatic copy number alterations in cancer samples. Though this is immensely useful to identify potential driver genes, it is not sufficient to identify genes acting in a concerted manner. In cancer cells, co-amplified genes have been shown to provide synergistic effects, and genomic alterations targeting a pathway have been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Biology
Share to Gene Dosage
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomics

Share to Loss of Heterozygosity

Share to Metabolic Networks and Pathways

Share to Ovarian Neoplasms

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 23913205
DOI: 10.1007/978-1-62703-547-7_2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Identifying associations between genomic alterations in tumors.PMID 23913205Read ↗

Copy Number Analysis Identifies Novel Interactions Between Genomic Loci in Ovarian CancerSemantic proximity Read ↗

Co-expression in tissue-specific gene networks links genes in cancer-susceptibility loci to known somatic driver genes.Semantic proximity Read ↗

Genome-wide single nucleotide polymorphism arrays as a diagnostic tool in patients with synchronous endometrial and ovarian cancer.Semantic proximity Read ↗

A computational procedure to identify significant overlap of differentially expressed and genomic imbalanced regions in cancer datasets.Semantic proximity Read ↗

Combination of gene expression and genome copy number alteration has a prognostic value for breast cancer.Semantic proximity Read ↗

Copy number variants in clinical next-generation sequencing data can define the relationship between simultaneous tumors in an individual patientSemantic proximity Read ↗

Genome-wide functional synergy between amplified and mutated genes in human breast cancer.Semantic proximity Read ↗

Co-expression in tissue-specific gene networks links genes in cancer-susceptibility loci to known somatic driver genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.