Article
Expression patterns of hypoxic markers at the invasive margin of colorectal cancers and liver metastases.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Dec 2009
Rajaganeshan R, Prasad R, Guillou P J, Scott N, Poston G, Jayne D G
Abstract excerpt
AIM: To understand the role of hypoxia in cancer progression of primary colorectal cancer and colorectal liver metastases. To look at associations of hypoxia with more aggressive phenotypes. METHODS: Archival tissue was retrieved from 55 patients and tissue micro arrays were constructed using tissue from the margin and the centre of the tumour. Hypoxia markers Hif-1alpha, Vegf, CA-9, VHL and Glut-1 were...
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