Article
Sex-specific effect of IL9 polymorphisms on lung function and polysensitization.
Genes and immunity - 1 Sept 2009
Aschard H, Bouzigon E, Corda E, Ulgen A, Dizier M-H, Gormand F, Lathrop M, Kauffmann F, Demenais F
Abstract excerpt
Sex differences in asthma-associated phenotypes are well known but the genetic factors that may account for these differences have received little attention. This study aimed to characterize sex-specific and pleiotropic genetic factors underlying four quantitative phenotypes involved in the main asthma physiopathological pathways: immunoglobulin E levels, a measure of polysensitization (SPTQ), eosinophil counts...
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