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Article

Treatment of Alport syndrome: beyond animal models.

Kidney international - 1 Sept 2009

Gross Oliver, Kashtan Clifford E

Abstract excerpt

Alport syndrome (AS) is a hereditary glomerulopathy due to abnormal composition of the glomerular basement membrane, leading to end-stage renal disease (ESRD). Studies of animal models of AS have suggested a variety of potentially effective therapies, but none of these has been definitely shown to prevent or delay ESRD in human AS. Studies in Alport mice suggest that angiotensin inhibition not only has...

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Identifiers

PMID: 19536083
DOI: 10.1038/ki.2009.223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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