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Article

Clinical and Genetic Characteristics of Atypical Hemolytic Uremic Syndrome in Children: A Chinese Cohort Study.

Nephron - 1 Jan 2021

Wu Dan, Chen Jiahui, Ling Chen, Chen Zhi, Fan Jianfeng, Sun Qiang, Meng Qun, Liu Xiaorong

Abstract excerpt

BACKGROUND: Atypical hemolytic uremic syndrome (aHUS) is a rare but critical illness. To this date, few studies have reported on the disease in Chinese children. METHODS: We studied a Chinese pediatric cohort to delineate the clinical characteristics, genotypes, and prognosis. Ninety-one patients with aHUS were enrolled in this study. RESULTS: Fifty-nine children (64.8%) had anti-complement-factor-H...

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PMID: 33873197
DOI: 10.1159/000513009

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