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Article

PRMT5 is required for cell-cycle progression and p53 tumor suppressor function.

Nucleic acids research - 1 Aug 2009

Scoumanne A, Zhang J, Chen X

Abstract excerpt

Protein arginine methyltransferases (PRMTs) mediate the transfer of methyl groups to arginines in proteins involved in signal transduction, transcriptional regulation and RNA processing. Tumor suppressor p53 coordinates crucial cellular processes, including cell-cycle arrest and DNA repair, in re...

Read the complete abstract on PubMed

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Share to Eukaryotic Initiation Factor-4E
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 19528079
DOI: 10.1093/nar/gkp516
PMCID: PMC2731901

Genes

PRMT5
CARM1
PRMT1
MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19528079-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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PRMT5 is required for cell-cycle progression and p53 tumor suppressor function.PMID 19528079Read ↗

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PRMT5 supports multiple oncogenic pathways in mantle cell lymphomaSemantic proximity Read ↗

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