Article
High level of alpha-synuclein mRNA in peripheral lymphocytes of patients with alcohol dependence syndrome.
Bulletin of experimental biology and medicine - 1 Nov 2008
Taraskina A E, Filimonov V A, Kozlovskaya Yu A, Morozova M N, Gaschin D V, Schwarzman A L
Abstract excerpt
The content of mRNA for alpha-synuclein (a key protein of the dopaminergic system) was elevated in the peripheral lymphocytes of patients with alcohol dependence syndrome. Increased level of alpha-synuclein mRNA was not associated with changes in the expression of NR4A2 gene encoding Nurrl, one of the main transcription factors of dopaminergic neurons.
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